Prescribing TRUVADA for a PrEP Indication
TRUVADA for a PrEP indication must only be prescribed as part of a comprehensive prevention strategy that includes other prevention measures, such as safer sex practices, because TRUVADA is not always effective in preventing the acquisition of HIV-1. Counsel uninfected individuals about safer sex practices that include:
- Consistent and correct use of condoms
- Limiting the number of sexual partners
- Knowledge of their HIV-1 status and that of their partner(s)
- Regular testing for other sexually transmitted infections that can facilitate HIV-1 transmission (such as syphilis and gonorrhea)
Uninfected individuals should also be counseled to strictly adhere to the recommended daily dosing schedule. The effectiveness of TRUVADA in reducing the risk of acquiring HIV-1 is strongly correlated with adherence as demonstrated by measurable drug levels in clinical trials. Here are the key steps in prescribing TRUVADA for a PrEP indication. For a complete list of prescribing steps, review the Checklist for Prescribers.
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